Postpartum Medications

Type When/How Given Advantages Possible Side Effects/Disadvantages

Oxytocin (Pitocin)

Given after delivery of the placenta usually in IV bag or injection if no IV present.

Injection or one IV bag usually given after delivery to ensure that the uterus remains contracted and may prevent excessive bleeding.

Causes the uterus to contract.

Cramping.

Methergine

Given after delivery either orally or by injection. Often a series of six pills.

Given when excessive vaginal bleeding occurs.

Stronger than Oxytocin.

Cramping and nausea.

Contraindicated if high blood pressure problematic.

Carboprost Tromethamine

Given for excess bleeding that is not stopped by Pitocin and/or Methergine

Rapid Acting

Stronger than oxytocin

Nausea and vomiting

Use cautiously if have asthma, hypertension diabetes, or renal disease

Misoprostol Given rectally for excess bleeding Rapid acting and less side effects than Carboprost Tromethamine